PolyPhil

Areas of application
• Face (especially forehead, cheeks)
• Neck and décolleté
• Back of the hand
• Nerve areas

Treatment Protocol
• Injection technique: Linear retrograde or microdroplet
• Injection depth: Dermis
• Recommended sessions:
• Normal skin: 3 sessions spaced 14–21 days apart
• Mature skin: 4 sessions spaced 14–21 days apart
• Scars: 2 sessions spaced 14–21 days apart
• Dosage: 2 ml per session (for scars, max. 0.1–0.2 ml per point)

Composition
• 40 mg of highly purified polynucleotides (PN-HPT®) per 2 ml syringe
• Package contents: 1 x 2 ml syringe + 2 needles (30G x 13 mm)

PolyPhil – Biostimulation for Skin Rejuvenation of the Face, Neck, Décolleté, and Hands

PolyPhil (formerly PhilArt) is a highly pure, injectable polynucleotide serum for aesthetic skin regeneration. Developed by Croma-Pharma, it was specifically designed for the treatment of the face, neck, décolleté, and hands. The high concentration of polynucleotides supports natural cell renewal, improves skin elasticity, and increases skin moisture levels – for a visibly fresher and firmer complexion.

It is suitable for both normal and mature skin and can be used for photoaging, loss of elasticity, dryness, and to reduce scars. PolyPhil is not a filler, but rather a biostimulating agent that activates the skin's own regeneration processes.

Therapeutic Properties
• Highly concentrated polynucleotide serum (40 mg/2 ml)
• Intradermal application for normal, sensitive, or mature skin
• Stimulates fibroblast activity and collagen production
• Improves skin elasticity, structure, and moisture retention
• Effective in the treatment of scars
• Compatible with other aesthetic procedures (e.g., laser, peeling, needling, fillers, radiofrequency, surgery)
• Application as part of Croma's Skin Enhancement Technique (SET)

PolyPhil is an effective, non-volumizing solution for biological skin rejuvenation and hydration – for a smoother, more elastic, and visibly revitalized complexion.

PhilArt - Biostimulation for Radiant, Vital Skin

Tailor-Made Aesthetics with Polynucleotides
Every skin is unique – as are its needs, which arise from age, skin texture, and lifestyle. Individualized treatment is crucial to preserving and enhancing natural beauty. The PhilArt product range is based on highly purified polynucleotides and supports skin regeneration through targeted biostimulatory effects.

Mechanism of Action
Polynucleotides are natural biopolymers that trigger profound regenerative processes in the skin. Their injection activates the body's own synthesis of collagen and elastin – two essential structural proteins for tone and elasticity. Furthermore, polynucleotides promote skin hydration by improving the skin's ability to retain moisture. The result is a visibly smoother, more radiant, and more youthful-looking skin texture.

Versatile Applications
PhilArt can be used as a standalone therapy or to optimize other aesthetic treatments, such as: E.g.:
• Hyaluronic acid fillers
• PRP (Platelet Rich Plasma)
• Laser treatments (e.g., CO₂ laser)
• Microneedling
• Peels
• Minimally invasive surgical procedures

The treatment is suitable for all skin types and age groups – both preventatively and for correcting already visible signs of aging.

Safety and Tolerance
PhilArt is characterized by high biocompatibility and a very low risk of side effects. The products are based on purified, fragmented polynucleotides of non-animal origin and are subject to strict quality controls. Application is carried out exclusively by medical professionals.

PhilArt – for visibly regenerated skin that impresses with its natural appearance.
Discover the full potential of biostimulating aesthetics.

Croma-Pharma GmbH is an Austrian, family-run company based in Leobendorf near Vienna. Founded in 1976, Croma specializes in the manufacture and international distribution of products for minimally invasive aesthetic medicine – including hyaluronic acid fillers, botulinum toxin, PDO threads, biostimulators, and skincare. The company operates in over 80 countries and is one of the established providers in this field.