PolyPhil Next

Areas of application
• Face (especially forehead and cheeks)
• Neck and décolleté
• Back of the hands
• Sunken scars and stretch marks

Treatment Protocol
• Injection technique: Multi-puncture technique or linear-retrograde technique
• Injection depth: Dermis
• Recommended sessions:
• Normal skin: 3 sessions 14–21 days apart
• Mature skin: 4 sessions 14–21 days apart
• Scars/Striae: Adapted to the individual treatment goal

Composition & Packaging
• 20mg polynucleotides + 20mg hyaluronic acid per 2ml
• Package: 1 syringe (2ml) + 2 needles (30G x 13mm)

PolyPhil Next – Combined Biostimulation and Hydration for Face, Neck, Décolleté, and Hands

PolyPhil Next (formerly PhilArt Next) is an injectable serum for aesthetic skin regeneration, developed by Croma-Pharma. It combines highly purified polynucleotides with non-crosslinked hyaluronic acid to specifically improve skin texture, promote cell renewal, and stabilize the skin's moisture balance over the long term.

The formulation is suitable for the treatment of the face, neck, décolleté, and back of the hands. PolyPhil Next is indicated for skin rejuvenation as well as for the reduction of depressed scars and stretch marks. The therapy can be used alone or as a preparatory measure before further aesthetic or surgical procedures.

Therapeutic Properties
• Combination of polynucleotides (20 mg) and hyaluronic acid (20 mg) per 2 ml
• Intradermal application for normal, sensitive, and mature skin
• Stimulates fibroblast activity and collagen regeneration
• Improves skin elasticity, moisture retention, and structure
• Supports regeneration of scars and stretch marks
• Suitable for skin preparation for laser, peel, filler, needling, RF, or surgical procedures
• Application according to the Skin Enhancement Technique (SET) developed by Croma

Safety
PolyPhil Next is very well tolerated. Mild irritation or pain at the injection site may occur, but usually subsides within a few days. According to the manufacturer, no serious side effects are known.

PolyPhil Next offers an effective combination of biostimulation and hydration for a firmer, smoother, and visibly rejuvenated complexion – with natural results and high tolerability.

PhilArt - Biostimulation for Radiant, Vital Skin

Tailor-Made Aesthetics with Polynucleotides
Every skin is unique – as are its needs, which arise from age, skin texture, and lifestyle. Individualized treatment is crucial to preserving and enhancing natural beauty. The PhilArt product range is based on highly purified polynucleotides and supports skin regeneration through targeted biostimulatory effects.

Mechanism of Action
Polynucleotides are natural biopolymers that trigger profound regenerative processes in the skin. Their injection activates the body's own synthesis of collagen and elastin – two essential structural proteins for tone and elasticity. Furthermore, polynucleotides promote skin hydration by improving the skin's ability to retain moisture. The result is a visibly smoother, more radiant, and more youthful-looking skin texture.

Versatile Applications
PhilArt can be used as a standalone therapy or to optimize other aesthetic treatments, such as: E.g.:
• Hyaluronic acid fillers
• PRP (Platelet Rich Plasma)
• Laser treatments (e.g., CO₂ laser)
• Microneedling
• Peels
• Minimally invasive surgical procedures

The treatment is suitable for all skin types and age groups – both preventatively and for correcting already visible signs of aging.

Safety and Tolerance
PhilArt is characterized by high biocompatibility and a very low risk of side effects. The products are based on purified, fragmented polynucleotides of non-animal origin and are subject to strict quality controls. Application is carried out exclusively by medical professionals.

PhilArt – for visibly regenerated skin that impresses with its natural appearance.
Discover the full potential of biostimulating aesthetics.

Croma-Pharma GmbH is an Austrian, family-run company based in Leobendorf near Vienna. Founded in 1976, Croma specializes in the manufacture and international distribution of products for minimally invasive aesthetic medicine – including hyaluronic acid fillers, botulinum toxin, PDO threads, biostimulators, and skincare. The company operates in over 80 countries and is one of the established providers in this field.