RESTYLANE Refyne

For the treatment of moderate to deep wrinkles

• Nasolabial folds
• corner of the mouth
• marionette lines
• Rhinoplasty
• forehead wrinkles
• tear trough
• glabellar lines

Injection depth:
middle dermis

Duration of effect:
up to 12 months, at least 18 months with follow-up treatment

Composition:
Cross-linked hyaluronic acid 20 mg/ml with lidocaine (0.3%)

Technology:
BT (Balance Technology)

Dosage form:
prefilled syringe

Package contents:
1 prefilled syringe of 1.00 ml

Needles/cannulas:
2 cannulas 27G ½” (Thin Wall Needle)

Benefits of Restylane® Refyne

• Natural results: Maintains the natural facial expressions and mobility so that patients can continue to maintain their expressiveness.
• Flexibility: The special composition is ideal for dynamic facial areas such as lips, nasolabial folds and marionette lines.
• Effective wrinkle reduction: Particularly effective in treating nasolabial folds, marionette lines and fine lines around the eyes and lips.
• Long-lasting results: Visible improvements that can last up to 12 months. With a follow-up treatment, the effect can even be extended up to 18 months.*
• Increased patient comfort: Contains lidocaine for pain relief, making treatment more comfortable for both patient and provider.

* Narins RS et al. Dermatol Surg 2008;34:S. 2-8; Rzany B et al. Dermatol Surg 2017;43:S. 58-65.


Why choose Restylane® Refyne?

Restylane® Refyne is the perfect choice for practitioners who want to offer their patients a flexible and versatile solution for wrinkle treatment. The targeted application allows individual needs to be met, giving patients a more youthful and refreshed appearance. The long-lasting and natural results make Restylane® Refyne a popular filler in aesthetic medicine.

Restylane® is considered a pioneer among non-animal, stabilized hyaluronic acid dermal fillers because it delivers immediately visible and long-lasting results. Since its launch in 1996, over 50 million successful applications have been carried out worldwide. Restylane®'s diverse product range enables precise adjustment to improve and define facial contours to achieve individualized results.

Innovations in hyaluronic acid filler technology

Since the introduction of Restylane® as the first synthetic, stabilized hyaluronic acid filler, the safety and efficacy standards of dermal fillers have increased significantly. Previous hyaluronic acid gels derived from animal sources were associated with a potentially increased risk of immune reactions. By using non-animal hyaluronic acid, Restylane® has minimized this risk.

Hyaluronic acid, a natural component of the human body, has the unique ability to bind thousands of times its own weight in water, which contributes to hydration and elasticity of tissue. Unlike the natural hyaluronic acid in the body, the stabilized form used by Restylane® is converted into a three-dimensional network using a special cross-linking technology. This structure imitates natural hyaluronic acid while ensuring longer durability, resulting in results that can last up to 24 months after just one treatment.

Restylane®: The benchmark for hyaluronic acid dermal fillers

Through continuous innovation and the highest quality standards, Restylane® has established itself as a leading provider in the world of hyaluronic acid fillers. Over 50 million treatments worldwide underline the outstanding position of Restylane® in aesthetic medicine.

Individualized treatment success thanks to Restylane® technologies

With advanced NASHA™ and BT™ technologies, Restylane® offers a diverse range of dermal fillers that enable customized aesthetic results.

• Restylane® BT™ gels: The exceptional softness and flexibility of these gels make them ideal for volume correction in the midface and contouring in dynamic facial areas such as lips and cheek folds. They are particularly suitable for patients with thinner tissue who prefer a gentler approach.

• Restylane® NASHA™ gels: These gels have a firm consistency and are used for projection and definition, e.g. to highlight the cheekbones, improve the chin and jawline and to reduce wrinkles. NASHA™ gels are characterized by a composition that is closer to natural hyaluronic acid than other fillers on the market.

The diverse properties of Restylane® fillers – from flexibility to strength – allow practitioners to tailor treatment to the individual needs of their patients in order to achieve the best possible customized treatment results.

Galderma is a global leader specializing in dermatology. With over 40 years of tradition in science-based innovation, Galderma offers a broad portfolio of brands and services covering all aspects of dermatology. The company has a strong position in the areas of Aesthetic Medicine, Dermatological Skin Care and Therapeutic Dermatology.

More information: https://www.galdermaaesthetics.com/